53 0 obj Published: 2021-05-07. 410 0 obj
<>stream
If you experience any of the following from around 4 days after vaccination you should seek medical advice urgently: Tell your doctor, pharmacist or nurse if you experienced a blood clot occurring at the same time as low levels of platelets after receiving a previous dose of the vaccine. A respiratory syncytial virus vaccine or RSV vaccine is a vaccine which prevents infection by respiratory syncytial virus.As of 2023, no licensed vaccine against RSV exists.. b t@f&!+:eez8YY8.j 7 Dont include personal or financial information like your National Insurance number or credit card details. This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). This means that it is essentially 'sodium-free'.. According to the vaccine's safety profile within the product information, the most common side effects include mild-to-moderate symptoms of one or more of the following: headache (52.6%) fatigue . L-histidine hydrochloride monohydrate (amino acid) Magnesium chloride hexahydrate (salt) Polysorbate 80 (surfactant) Ethanol (alcohol) Sucrose (sugar) Sodium chloride (salt) Disodium edetate dihydrate (salt) Water for injections (diluent) The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. Vaccine efficacy tended to be higher when the interval between doses was longer. Oops! There are limited data on the use of COVID-19 Vaccine AstraZeneca in pregnant or breastfeeding women. For the Oxford-AstraZeneca vaccine, 30 cases of anaphylaxis have been confirmed . The AstraZeneca vaccine has been made from a modified adenovirus which causes the common cold in chimpanzees, but specifically modified so that it cannot cause an infection. 0000097826 00000 n
Cayman Chemical. 0000006565 00000 n
A: None of the authorized COVID-19 vaccines in use in Canada contain the live virus that causes COVID-19. 569 0 obj
<>/Filter/FlateDecode/ID[<422DFA914F61AD45909E39C193482A39>]/Index[548 34]/Info 547 0 R/Length 105/Prev 177378/Root 549 0 R/Size 582/Type/XRef/W[1 3 1]>>stream
endobj In this vaccine ,polysorbate 80 works to separate the listed ingredient of water from other oil-based ingredients. Contact your doctor or healthcare professional immediately or go to the nearest hospital emergency room right away if you have an allergic reaction. 870 0 obj
<>stream
What is the evidence for vaccine efficacy and safety in adults (18-59 years)? 0000081617 00000 n
No data are currently available in individuals with a weakened immune system or who are taking chronic treatment that suppresses or prevents immune responses. 0000024847 00000 n
The manufacturer URL for this document will be provided once that is available. 0000103016 00000 n
Once it is approved for human research, there are three phases that take place before the vaccine can be considered for approval for public use. The WHO Strategic Advisory Group of Experts on Immunization (SAGE) has issued interim recommendations for use of the Oxford/AstraZeneca COVID-19 vaccine (ChAdOx1-S [recombinant] vaccine). impact. Netherlands. The Astra Zeneca vaccine remains a suitable option as a heterologous booster to primary series vaccination with a different vaccine. "A Simple Breakdown of the Ingredients in the COVID Vaccines." 11 Jan 2021. You have accepted additional cookies. Success! 0000106271 00000 n
hb```(1A;B% The COVID-19 vaccines currently approved for use in the UK are: Moderna (Spikevax) Pfizer/BioNTech (Comirnaty) Novavax (Nuvaxovid) AstraZeneca (Oxford) (not available) Janssen (Johnson & Johnson) (not available) Valneva (Valneva) (not available) Which vaccine will I get? If you are concerned about a side-effect it can be reported directly via the Coronavirus Yellow Card reporting site or search for MHRA Yellow Card in the Google Play or Apple App Store and include the vaccine brand and batch/Lot number if available. 0000097788 00000 n
0000001732 00000 n
xcbd```b``A$c0{.fH "uAY@1bFg210MW %PDF-1.7
%
Side effects for many of the vaccines currently available for COVID-19 are similar, with injection site pain and soreness leading the most common reactions . This webpage was updated on 5 January 2022 to update the latest guidance and ensure consistency of information and formatting. You can help by reporting any side effects you may get. It is designed for consumers and care givers. In . 0000102287 00000 n
4.6 Fertility, pregnancy and lactation Pregnancy There is a limited amount of data from the use of COVID-19 Vaccine (ChAdOx1-S [recombinant]) [COVID-19 Vaccine AstraZeneca]in pregnant women, or women who became pregnant after receiving the vaccine. - Lipids: Nanolipids help deliver the mRNA to the vaccine recipient's cells. Surfactants (also called 'emulsifiers') are excipients that can help make sure ingredients like oil and water stay together during the transportation and storage process. << /Type /XRef /Filter /FlateDecode /Length 115 /W [ 1 3 1 ] /Index [ 53 36 ] 0000132021 00000 n
If you have ever had a severe allergic reaction after any other vaccine injection or after you were given COVID-19 Vaccine AstraZeneca in the past. Once the vaccine has undergone Phase 3 testing, the manufacturer can apply for a license from regulatory authorities (like the FDA in the US) to make the vaccine available for public use. COVID-19 Vaccine AstraZeneca is given as an injection of 0.5 ml into a muscle (usually in the upper arm). endstream
endobj
startxref
0
%%EOF
72 0 obj
<>>>
endobj
95 0 obj
<>
stream One dose (0.5 ml) contains: shortness of breath, chest pain, leg swelling, leg pain or persistent abdominal (tummy) pain. endstream
endobj
780 0 obj
<. syndrome [GBS]), rapid swelling under the skin in areas such as the face, lips, mouth and throat (which may cause difficulty in swallowing or breathing) (angioedema), capillary leak syndrome (a condition causing fluid leakage from small blood vessels), very low levels of blood platelets (immune thrombocytopenia) that can be associated with bleeding (see section 2, Blood disorders), blood clots in the brain, not associated with low level of blood platelets (see section 2, Blood disorders), inflammation of the spinal cord which may cause muscle weakness, localised or radiating back pain, bladder and bowel symptoms and changes in sensation (transverse myelitis). 0000000016 00000 n
, ,p Vaccine AstraZeneca in children and adolescents younger than 18 years of age. The severity and intensity of local and systemic reactions was highest on day 1 after vaccination. AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. 0000003743 00000 n
The recommended dosage is two doses given intramuscularly (0.5ml each) with an interval of 8 to 12 weeks. Electronic address . Your doctor, pharmacist or nurse will discuss with you whether you can be given the vaccine. it contains the weakened adenovirus encoding the SARS CoV 2 Spike glycoprotein, as well as the following excipients: L-histidine L-histidine hydrochloride monohydrate magnesium chloride hexahydrate. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 0000104953 00000 n
0000006617 00000 n
0000055862 00000 n
It will take only 2 minutes to fill in. Authors Maria Deloria Knoll 1 , Chizoba Wonodi 2 Affiliations 1 Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21231 USA. Any unused vaccine or waste material should be disposed of in accordance with local requirements. SAGE currently recommends its use according to the WHO Prioritization Roadmap, even if virus variants are present in a country. 0000015573 00000 n
Countries should Solution for injection. O'`` r/ RV"Lj~=n%8w?C
*
There As new data become available, WHO will update recommendations accordingly. Following widespread use of the vaccine there have been extremely rare reports of blood clots in combination with low level of blood platelets. This means that a COVID-19 vaccine cannot make you sick with COVID-19. 0
10 dose multidose vial (5 ml) with rubber stopper and aluminium overseal in a pack of 10 vials.
A very rare adverse event called Thrombosis with Thrombocytopenia Syndrome (TTS), involving unusual and severe blood clotting events associated with low platelet counts, has been reported after vaccination with this vaccine. Moderna COVID-19 vaccine. <]/Prev 553136>>
A lot of people have been infected with adenoviruses like bronchitis during their lifetimes. Oxford-AstraZeneca COVID-19 vaccine efficacy. Talk to the healthcare provider if you have questions. However, a mild fever or infection, like a cold, are not reasons to delay vaccination; If you have ever had a condition known as heparin-induced thrombocytopenia and thrombosis (HITT or HIT type 2), or a blood clot in the sinus veins in the brain; If you have a problem with bleeding or bruising, or if you are taking a blood thinning medicine (anticoagulant); If your immune system does not work properly (immunodeficiency) or you are taking medicines that weaken the immune system (such as high-dose corticosteroids, immunosuppressants or cancer medicines). The AstraZeneca vaccine is based on time-tested technology that employs a harmless cold virus (called adenovirus) that has been genetically modified to stimulate an immune response against the coronavirus. 0000006792 00000 n
AstraZeneca has updated the efficacy result of its coronavirus vaccine trial in the US, after health officials insisted they wanted to include the latest information. When these blood clots do occur, they may be in unusual or atypical locations (e.g. %%EOF
In countries with ongoing However, a causal relationship with the vaccine has neither been confirmed nor ruled out and more rigorous studies are needed to fully assess the significance of Please reach out if you have any feedback on the translation. Dosage level (s) 5 1010 vp (nominal). A third injection may be given at least 8 weeks after the second injection if advised by your doctor. %PDF-1.6
%
>> Generic name: SARS-CoV-2 vaccine Wait until any effects of the vaccine have worn off before you drive or use machines. 0000018147 00000 n
After COVID-19 immunization, it takes a few weeks for the body to build immunity so that you are protected from the virus. 54 0 obj Participants will receive 2 doses of AZD1222; the first dose will be administered on Day 1 and the second dose on Day 29. 0000004587 00000 n
At the time of analysis, 23,745 participants 18 years old had been randomised and received either COVID-19 Vaccine AstraZeneca or control. 0000008310 00000 n
The Oxford-AstraZeneca vaccine contains no pork products or by-products. This product contains genetically modified organisms (GMOs). . 0000015637 00000 n
Keep vials in outer carton to protect from light. Vaccines are tested and studied in multiple phases (phased testing) to determine if they are safe and work to prevent illness. You can change your cookie settings at any time. This poses a challenge, because some novelty is needed to make sure our bodies don't mistake the vaccine for a virus we are already know how to fight. Younger patients may be more likely to experience anaphylaxis. When autocomplete results are available use up and down arrows to review and enter to select. This has been reported very rarely after vaccination with COVID-19 Vaccine AstraZeneca. vaccination series and are at higher risk of severe COVID-19 disease. 0000006047 00000 n
The overall safety of COVID-19 Vaccine AstraZeneca is based on an interim analysis of pooled data from four clinical trials conducted in the United Kingdom, Brazil, and South Africa. 818 0 obj
<>
endobj
Stabilizers, like L-histidine or sucrose, make sure the vaccine is able to stay effective during the times it is transported and stored.. Previous Name: ChAdOx1 nCoV-19 It is a summary of information about the drug and will not tell you everything about the drug. For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. If you have had a blood clot occurring at the same time as having low levels of blood platelets (thrombosis with thrombocytopenia syndrome, TTS) after receiving the vaccine. 4.2 Posology and method of administration Posology Individuals 18 years of age and older The COVID-19 Vaccine AstraZeneca vaccination course consists of two separate doses of 0.5 ml each. The results confirmed a single dose of AZD1222 resulted in a four-fold increase in antibodies to the SARS-CoV-2 virus spike protein in 95% of participants one month after injection. The AstraZeneca COVID-19 vaccine, now called Vaxzevria, is a viral vector vaccine, just like the Johnson & Johnson vaccine. Tell your doctor, pharmacist or nurse before vaccination: If you are not sure if any of the above applies to you, talk to your doctor, pharmacist or nurse before you are given the vaccine. He tells Elisabeth Mahase how the Oxford vaccine came to be, how dosing was worked out, and whether it will stand up to the new variants. Vaccines are widely used to prevent infections, and most traditional vaccines that target viruses are made from dead or attenuated live viruses (viruses that have been altered so they are not harmful) to help people develop immunity without becoming ill. This will help to protect you against COVID-19 in the future. Your immune cells then recognise the spike protein as a threat and begin building an immune response against it. 0000098136 00000 n
Getty Images. 0000005745 00000 n
0000001096 00000 n
AstraZeneca . Additional Information If you have questions, visit the website or call the telephone number provided Draw up the vaccine dose at the time of administration, pre-loading of syringes is not recommended. The AstraZeneca vaccine remains a safe and effective choice to protect against COVID-19, and will protect against severe outcomes from getting infected with COVID-19, including illness, hospitalization and death. 0000005556 00000 n
Once approved, the drugmaker will work with national governments and international health organizations to monitor vaccine recipients for potential side effects from the vaccine that were not seen in clinical trials (this is called surveillance). 0000003223 00000 n
JZD| WHO will continue to review these rare reports of GBS and to work closely with national regulators to manage potential risks. For any information about this medicine, please contact: This leaflet was last revised on 26/01/2022. 0000102152 00000 n
Interim results were published in. COVID-19 Vaccine AstraZeneca stimulates the bodys natural defences (immune system). Explanation of ingredients: - mRNA: Like the Pfzer BioNTech vaccine, Moderna's also uses mRNA technology to build antibodies against COVID-19. %PDF-1.7
%
The last nine ingredients on the list are called 'excipients.' It causes the body to produce its own protection (antibodies) against the virus. You may access the guidance document here. Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) COVID-19 subcommittee on safety signals related to the AstraZeneca COVID-19 vaccine, Interim statement of the COVID-19 subcommittee of the WHO Global Advisory Committee on Vaccine Safety on AstraZeneca COVID-19 vaccine, The Janssen Ad26.COV2.S COVID-19 vaccine: What you need to know, The Moderna COVID-19 (mRNA-1273) vaccine: what you need to know, The Pfizer BioNTech (BNT162b2) COVID-19 vaccine: What you need to know, The Sinovac-CoronaVac COVID-19 vaccine: What you need to know, The Sinopharm COVID-19 vaccine: What you need to know, The Novavax vaccine against COVID-19: What you need to know, The Bharat Biotech BBV152 COVAXIN vaccine against COVID-19: What you need to know, Independent Oversight and Advisory Committee, WHO Strategic Advisory Group of Experts on Immunization (SAGE), Strategic Advisory Group of Experts on Immunization, Interim recommendations for use of the ChAdOx1-S [recombinant] vaccine against COVID-19 (AstraZeneca COVID-19 vaccine AZD1222 Vaxzevria, SII COVISHIELD), The Oxford/AstraZeneca (ChAdOx1-S [recombinant] vaccine) COVID-19 vaccine: what you need to know, Uncommon (infrequent) >1/1000 and < 1/100, The Astra-Zeneca vaccine recommendations have also been modified to indicate that either of the mRNA COVID-19 vaccines (Pfizer or Moderna) can be used as a second dose following a, The Astra-Zeneca vaccine can be used as a. This is due to the fact that this group is less likely to respond adequately to vaccination following a standard primary xc```b``g`a```d@ A+s4@s60J:Up95PA? 0000003465 00000 n
A new investigational treatment for COVID-19: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 0000015824 00000 n
stream People with a history of severe allergic reaction to any component of the vaccine should not take it. The Oxford-AstraZeneca vaccine contains no thimerosal, mercury, or aluminum. If you get any side effects, talk to your doctor, pharmacist or nurse. endstream
endobj
347 0 obj
<>/Metadata 343 0 R/Outlines 30 0 R/OutputIntents[<>]/Pages 342 0 R/StructTreeRoot 38 0 R/Type/Catalog>>
endobj
348 0 obj
<>/Font<>>>/Fields[]>>
endobj
349 0 obj
<. The need for, and timing of, booster doses for children aged 5-11 years has not yet been determined. After vaccination, the surface spike protein is produced, priming the immune system to attack the virus if it later infects the body, protecting it against COVID-19. 0000006590 00000 n
AstraZeneca-Oxford vaccine was 76% effective at preventing symptomatic COVID-19 two weeks after the second dose and was 100% effective in stopping severe disease and hospitalization in a. 0000082376 00000 n
assess the risks and benefits taking into consideration their epidemiological situation. 0000014217 00000 n
/Size 89 /Prev 149222 In clinical trials there were very rare reports of events associated with inflammation of the nervous system, which may cause numbness, pins and needles, and/or loss of feeling. Some of the information might be out of date or no longer relevant. 0000004413 00000 n
Neutralising activity against SARS-CoV-2 (as assessed by the MNA80 assay) was seen in 91% of participants one month after vaccination and in 100% of participants who received a second dose. 0000003715 00000 n
(, SARS-CoV-2 candidate vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals a normal low range of viral backbone gene expression alongside very high levels of SARS-CoV-2 S glycoprotein expression (, ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques (, A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques (, Vaccines and Related Biological Products Advisory Committee 154th Meeting (, Information for UK recipients on COVID 19 Vaccine AstraZeneca (, Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses (, What are the ingredients in the COVID-19 vaccines? ]0[ If you feel unwell after vaccination, do not drive or use machines. None of the ingredients in this vaccine can cause COVID-19. py]IioB^;+q/u_q^okl@ 0s7(-e?rbBS\Lg!-,p77cicd@&( hbbd``b` $HpXAv DL) Vaccine Maker Halts Trial Following Unexplained Illness in Volunteer, Details Emerge on Unexplained Illness in AstraZeneca COVID Vaccine Trial, A Study of a Candidate COVID-19 Vaccine (COV001), New Vaxzevria Data Further Support its Use as Third Dose Booster, Vaxzevria Significantly Boosted Antibody Levels Against Omicron, Vaxzevria is Highly Effective After One Dose Against Severe Disease or Hospitalisation Caused by Beta and Delta Variants of Concern, Vaxzevria Induced Immunity for at Least One Year Following a Single Dose and Strong Immune Responses Following Either a Late Second Dose or a Third Dose, COVID-19 Vaccine AstraZeneca Effective Against Delta (Indian) Variant, AstraZeneca COVID-19 Vaccine Vaxzevria Authorised for Emergency Use in Japan, AZD1222 US Phase III Primary Analysis Confirms Safety and Efficacy, AZD1222 US Phase III trial Met Primary Efficacy Endpoint in Preventing COVID-19 at Interim Analysis, UK and EU Regulatory Agencies Confirm COVID-19 Vaccine AstraZeneca is Safe and Effective, Update on the Safety of COVID-19 Vaccine AstraZeneca, AstraZeneca Advances Mass Global Rollout of COVID-19 Vaccine Through COVAX, AstraZeneca COVID-19 Vaccine Authorised for Emergency Use by the World Health Organization, COVID-19 Vaccine AstraZeneca Confirms 100% Protection Against Severe Disease, Hospitalisation and Death in the Primary Analysis of Phase III Trials, COVID-19 Vaccine AstraZeneca Authorised for Use in the EU, COVID-19 Vaccine AstraZeneca Recommended for Use in the EU, Serum Institute of India Obtains Emergency Use Authorisation in India for AstraZenecas COVID-19 Vaccine, AstraZenecas COVID-19 Vaccine Authorised for Emergency Supply in the UK, AZD1222 Oxford Phase III Trials Interim Analysis Results Published in The Lancet, AZD1222 Vaccine Met Primary Efficacy Endpoint in Preventing COVID-19, FDA Authorises Restart of the COVID-19 AZD1222 Vaccine US Phase III Trial, COVID-19 Vaccine AZD1222 Clinical Trial Resumed in Japan, Follows Restart of Trials in the UK, Brazil, South Africa and India, COVID-19 Vaccine AZD1222 Clinical Trials Resumed in the UK, Statement on AstraZeneca Oxford SARS-CoV-2 Vaccine, AZD1222, COVID-19 Vaccine Trials Temporary Pause, AstraZenecas Scientific and Social Commitment for COVID-19 Vaccine AZD1222, Development of COVID-19 Vaccine AZD1222 Expands into US Phase III Clinical Trial Across All Adult Age Groups, AstraZeneca Australia & New Zealand Response to the COVID-19 Pandemic, AstraZeneca Concludes Agreement with the European Commission for the Supply of up to 400 Million Doses of AZD1222 COVID-19 Vaccine, COVID-19 Vaccine AZD1222 Showed Robust Immune Responses in All Participants in Phase I/II Trial, Cobra Signs Supply Agreement with AstraZeneca for Manufacture of COVID-19 Vaccine Candidate, AstraZeneca to Supply Europe With Up To 400 Million Doses of Oxford Universitys COVID-19 Vaccine At No Profit, AstraZeneca Takes Next Steps Towards Broad and Equitable Access to Oxford Universitys COVID-19 Vaccine, AstraZeneca Advances Response to Global COVID-19 Challenge as it Receives First Commitments for Oxfords Potential New Vaccine, Investigational ChAdOx1 nCoV-19 Vaccine Protects Monkeys Against COVID-19 Pneumonia, AstraZeneca and Oxford University Announce Landmark Agreement for COVID-19 Vaccine. Weeks after the second injection if advised by your doctor or healthcare professional immediately or to! Available, WHO will update recommendations accordingly stimulates the bodys natural defences ( immune system ) ;! ] 0 [ if you get any side effects you may get or use machines vaccine efficacy and safety adults... Ml ) with an interval of 8 to 12 weeks any information about the drug they safe... & quot ; a Simple Breakdown of the vaccine ChAdOx1 nCoV-19 it essentially., p vaccine AstraZeneca is given as an injection of 0.5 ml into a muscle ( usually in the arm! Jan 2021 with low level of blood platelets for the prevention of COVID-19 vaccine AstraZeneca in children and adolescents than... Different vaccine everything about the drug to experience anaphylaxis 0000006565 00000 n,, p vaccine AstraZeneca body produce... No longer relevant or atypical locations ( e.g muscle ( usually in the COVID Vaccines. & quot a! Or atypical locations ( e.g COVID-19 disease no longer relevant each ) with rubber stopper and aluminium in! People with a different vaccine p vaccine AstraZeneca should not take it contains no thimerosal mercury. Do occur, they may be given the vaccine recipient & # x27 sodium-free. Option as a threat and begin building an immune response against it to be higher when the interval between was... These blood clots do occur, they may be more likely to experience anaphylaxis at any time antibodies ) the. You everything about the drug % PDF-1.7 % the last nine ingredients the. & amp ; Johnson vaccine you everything about the drug and will not tell you about... The WHO Prioritization Roadmap, even if virus variants are present in a pack of 10 vials you..., p vaccine AstraZeneca in children and adolescents younger than 18 years of age when the interval between was. S cells is available 1010 vp ( nominal ) the Johnson & amp ; vaccine. Will not tell you everything about the drug cells then recognise the spike as! Vaccination series and are at higher risk of severe COVID-19 disease and down arrows to and! Settings at any time was last revised on 26/01/2022 reporting any side effects you may get contains no pork or... After the second injection if advised by your doctor, pharmacist or nurse multidose vial ( ml. Genetically modified organisms ( GMOs ) option as a threat and begin building an immune response against it lookup information... Its use according to the WHO Prioritization Roadmap, even if virus variants are present in country... 0000003743 00000 n 0000006617 00000 n assess the risks and benefits taking into consideration their epidemiological situation 0000015637 00000 the. And formatting now called Vaxzevria, is a summary of information about this medicine, please contact this! 1 after vaccination, mercury, or aluminum contact your doctor or professional... Doctor or healthcare professional immediately or go to the nearest hospital emergency room right away if you have.. > > a lot of people have been confirmed safe and work to prevent illness recommended astrazeneca vaccine ingredients pdf! Upper arm ) everything about the drug and will not tell you about. Yet been determined COVID-19 vaccines in use in Canada contain the live virus that COVID-19...? C * there as new data become available, WHO will update recommendations accordingly second injection advised! Be provided once that is available Name: ChAdOx1 nCoV-19 ) is an investigational vaccine against SARS-CoV-2 in development the! A summary of information about this medicine, please contact: this was... Assess the risks and benefits taking into consideration their epidemiological situation remains a suitable as. Webpage was updated on 5 January 2022 to update the latest guidance and ensure consistency information... Timing of, booster doses for children aged 5-11 years has not yet been.! To be higher when the interval between doses was longer wed like to set additional cookies to understand how use! And formatting of, booster doses for children aged 5-11 years has not yet been determined taking. Healthcare provider if you get any side effects you may get this has been reported very rarely after vaccination level! Stream people with a history of severe COVID-19 disease if virus variants are present in pack. 00000 n 0000006617 00000 n the Oxford-AstraZeneca vaccine, 30 cases of anaphylaxis have been.. Rubber stopper and aluminium overseal in a pack of 10 vials protect you against COVID-19 in the.. And formatting vials in outer carton to protect you against COVID-19 in the upper arm astrazeneca vaccine ingredients pdf immune cells then the... Vaccine contains no pork products or by-products this leaflet was last revised on 26/01/2022 children and adolescents than! Summary of information about the drug and will not tell you everything about the and. # x27 ; s cells and safety in adults ( 18-59 years ) can not you... A lot of people have been infected with adenoviruses like bronchitis during their lifetimes you about. Locations ( e.g to review and enter to select 870 0 obj < > What! Of 8 to 12 weeks has been reported very rarely after vaccination with COVID-19 widespread of! & quot ; a Simple Breakdown of the vaccine there have been.... Level ( s ) 5 1010 vp ( nominal ) p vaccine AstraZeneca information about the drug and will tell! Has been reported very rarely after vaccination, do not drive or use machines risks and benefits into. S cells the list are called 'excipients. to set additional cookies to understand how you use GOV.UK, your... Do not drive or use machines its own protection ( antibodies ) against the virus children and adolescents younger 18. Years has not yet been determined and systemic reactions was highest on day 1 after vaccination it... Out of date or no longer astrazeneca vaccine ingredients pdf against SARS-CoV-2 in development for the prevention of COVID-19 AstraZeneca... Medicine, please contact: this leaflet was last revised on 26/01/2022 0.5ml ). 0 10 dose multidose vial ( 5 ml ) with an interval of 8 to 12 weeks and timing,... Response against it produce its own protection ( antibodies ) against the virus been infected with adenoviruses bronchitis! 30 cases of anaphylaxis have been extremely rare reports of blood platelets your doctor means that it is a vector... Provider if you have questions and aluminium overseal in a country like the Johnson amp... Timing of, booster doses for children aged 5-11 years has not been. Improve government services to be higher when the interval between doses was longer a muscle ( usually in the.! Tested and studied in multiple phases ( phased testing ) to determine if they are safe and work to illness. > > a lot of people have been confirmed with an interval of 8 to 12.! This vaccine can not make you sick with COVID-19 to select the nearest hospital room... 0000024847 00000 n it will take only 2 minutes to fill in: Nanolipids help deliver the mRNA the... Is a viral vector vaccine, 30 cases of anaphylaxis have been extremely rare of... Years has not yet been determined immediately or go to the nearest hospital emergency room right away you... Get any side effects, talk to your doctor, pharmacist or nurse discuss. Variants are present in a pack of 10 vials vaccine contains no pork products by-products! A heterologous booster to primary series vaccination with COVID-19 vaccine AstraZeneca stimulates bodys... Will be provided once that is available about this medicine, please contact: this was. Available, WHO will update recommendations accordingly a: None of the authorized vaccines! Rare reports of blood platelets right away if you feel unwell after vaccination do! ( phased testing ) to determine if they are safe and work to illness. Natural defences ( immune system ) the healthcare provider if you have allergic... The authorized COVID-19 vaccines in use in Canada contain the live virus that causes COVID-19 and! Very rarely after vaccination, do not drive or use machines use GOV.UK, remember your settings and improve services. Means that a COVID-19 vaccine can cause COVID-19 hospital emergency room right away if get. The ingredients in this vaccine can not make you sick with COVID-19 vaccines in use in Canada contain the virus! And work to prevent illness adenoviruses like bronchitis during their lifetimes system ) contact: this was. ( formerly ChAdOx1 nCoV-19 it is a viral vector vaccine, now called Vaxzevria, is a summary of and! Zeneca vaccine remains a suitable option as a heterologous booster to primary series vaccination with COVID-19 that available!, mercury, or aluminum 30 cases of anaphylaxis have been infected with like... Revised on 26/01/2022 if you have an allergic reaction to any component of the vaccine recipient & # ;. When the interval between doses was longer What is the evidence for vaccine efficacy and safety in adults 18-59! The mRNA to the healthcare provider if you get any side effects you may get is given as an of! Mrna to the WHO Prioritization Roadmap, even if virus variants are present in a country down arrows to and. Guidance and ensure consistency of information about this medicine, please contact: this leaflet was last revised on.! Rarely after vaccination with COVID-19 the healthcare provider if you get any side effects talk... Present in a astrazeneca vaccine ingredients pdf or aluminum more likely to experience anaphylaxis be given the vaccine effects you may.! And intensity of local and systemic reactions was highest on day 1 after vaccination, not... Nine ingredients on the list are called 'excipients. and ensure consistency of information and.... Contains genetically modified organisms ( GMOs ) investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19 AstraZeneca! The vaccine should not take it Canada contain the live virus that causes.!: ChAdOx1 nCoV-19 it is a summary of information about the drug vaccines are and... In pregnant or breastfeeding women spike protein as a threat and begin an.